After saving New York the Ghostbusters company was shut down and they all went their own ways. But now, when the city is again in danger they have to overcome their differences and raise again to fight the dark forces.
Three eccentric scientists are sacked from their jobs at the university, so they decide to go private with their research into the ghost stories. When New York City is being invaded by thousands of ghosts of any kind... who you gonna call?
Senator Wilson, who tries to introduce limitations in access to firearms boards the train that will take him to his next meeting. Group of terrorists from paramilitary organization takes over the train and senator as hostage. Single ATF agent is onboard to save him and the passengers.